Date not given: When an anomaly strikes the ship, Archer is infected with parasites that frequently erase his short-term memory. 12 years later, he doesn't remember how T'Pol took command of the ship, how the Xindi destroyed Earth, and how the few surviving humans settled on Ceti Alpha V. In the meantime, Phlox has devised a therapy to destroy the parasites, which exist outside normal space-time, using a subspace implosion in a special chamber. The device is installed on Enterprise, now commanded by Captain Tucker. But the Xindi have located the human settlement and are attacking the system. Phlox finds out that the eradicated parasites don't only vanish in the present, but also in the past. When the chamber is damaged in the attack, Archer, Phlox and T'Pol set the warp core to overload to create the ultimate subspace implosion. The ship explodes, and the past is changed.

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