Stardate 50485.2: Sisko is going to retrieve information about the former Commander Eddington, who defected to the Maquis, when his contact turns out to be none other than Eddington himself. Eddington sabotages the Defiant with a cascade virus and escapes. Using a compound that is harmless to humans but hazardous to Cardassians, Eddington begins to poison Cardassian colonies. The Defiant now receives support from the USS Malinche, but the Maquis attack and disable the Starfleet ship. When his ship arrives too late to stop another attack on a Cardassian planet, Sisko decides to turn the tables and contaminate a Maquis planet with a chemical that is harmful to humans but not to Cardassians. While the two sides have to switch planets, Eddington turns himself over to the Federation authorities in order to avert a further escalation.

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